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👉📝WANT STUDY NOTES FOR THIS PRESENTATION? 👉Join Patreon at 🤍 Pharmacokinetics is the study of the movement of drugs within the body, often described as "what the body does to a drug". This pharmacology lecture covers topics such as absorption (passive diffusion, facilitated diffusion, active transport, endocytosis), distribution (volume), metabolism (phase I, phase II), elimination (zero, first-order kinetics), steady state, cytochrome P450 (inducers, inhibitors). Thanks for watching and don't forget to SUBSCRIBE, hit the LIKE button👍 and click the BELL button🔔 for future notifications!!! 0:00 Intro 1:45 Overview 2:32 Absorption 5:57 Distribution 8:07 Elimination 11:03 Metabolism
What are drugs? What do they do? How do they do what they do? These questions are part of the field of pharmacology, and over this series we will learn all about a wide variety of different drugs that have clinical use. This will require a lot of prerequisite knowledge in other fields, so make sure to check out some of my other playlists as well, but when you're ready, let's dive into the world of drugs! Watch the whole Pharmacology playlist: 🤍 General Chemistry Tutorials: 🤍 Organic Chemistry Tutorials: 🤍 Biochemistry Tutorials: 🤍 Biology/Genetics Tutorials: 🤍 Anatomy & Physiology Tutorials: 🤍 Biopsychology Tutorials: 🤍 Microbiology/Infectious Diseases Tutorials: 🤍 History of Drugs Videos: 🤍 Immunology Tutorials: 🤍 EMAIL► ProfessorDaveExplains🤍gmail.com PATREON► 🤍 Check out "Is This Wi-Fi Organic?", my book on disarming pseudoscience! Amazon: 🤍 Bookshop: 🤍 Barnes and Noble: 🤍 Book Depository: 🤍
👉📝WANT STUDY NOTES FOR THIS PRESENTATION? 👉Join Patreon at 🤍 Antihypertensives are a class of drugs that are used to treat hypertension. Antihypertensive therapy seeks to prevent the complications of high blood pressure such as heart attack and stroke. This pharmacology lecture covers topics such as pathophysiology of hypertension, regulation of blood pressure, cardiac output, systemic vascular resistance, baroreceptors, alpha & beta receptors, vasoconstriction, vasodilation, renin-angiotensin-aldosterone system, bradykinin, nitric oxide. Mechanism of action of antihypertensive drugs and their side effects; adrenergic antagonists; alpha & beta blockers, centrally acting adrenergic agents, dihydropyridine & nondihydropyridine calcium channel blockers, loop, thiazide, potassium-sparing diuretics, renin inhibitors, angiotensin converting enzyme (ACE) inhibitors, angiotensin II receptor type 1 blockers (ARBs), endothelin receptor antagonist, dopamine-1 receptor agonist, peripheral vasodilators. Drugs mentioned include; Doxazosin, Prazosin, Clonidine, Methyldopa, Amlodipine, Felodipine, Nicardipine, Nifedipine, Diltiazem, Verapamil, Furosemide, Hydrochlorothiazide, Triamterene, Spironolactone, Aliskiren, Benazepril, Captopril, Enalapril, Lisinopril, Quinapril, Ramipril, Candesartan, Irbesartan, Losartan, Olmesartan, Valsartan, Bosentan, Fenoldopam, Sodium Nitroprusside, Nitroglycerin, Hydralazine, and Minoxidil. Thanks for watching and don't forget to SUBSCRIBE, hit the LIKE button👍 and click the BELL button🔔 for future notifications!!! 0:00 Pathophysiology of hypertension 2:55 Alpha-1 blockers 3:10 Beta blockers 4:01 Centrally-acting adrenergic drugs 4:49 Calcium channel blockers 7:27 Diuretics 8:57 Inhibitors of renin-angiotensin-aldosterone system 12:25 Miscellaneous antihypertensives
Join Now! 🤍 In part 1 of 3, Kendall Wyatt MD, RN will help you understand how using drug endings can help you master Pharmacology faster, alongside Picmonic's research-proven learning system. Then watch Part 2 (🤍 to dig deep into the world of Beta Blockers, ACE-Inhibitors, calcium channel blockers and more! Get the playlist here: 🤍 TRY PICMONIC FOR FREE ► 🤍 Picmonic turns the information you need to know in nursing and medical school into unforgettable images and stories that are scientifically proven to increase memory retention! Join over 400,000 nursing and medical students using Picmonic’s Visual Learning Community to study and learn more effectively in less time. Picmonic is research-proven to increase test scores by 50% and long-term memory retention by 331% Picmonic for Nursing has you covered for your classes and the NCLEX® with subjects including Fundamentals, Pharmacology, Med-Surg, Anatomy, Physiology, Pediatrics, Obstetrics, Psychiatric, and more!. Picmonic for Medicine has you covered for USMLE Step 1 and Step 2 CK, with subject including Pathology, Pharmacology, Microbiology, Biochemistry, Psychiatry, Anatomy, Physiology, Epidemiology, and more! LET’S CONNECT! General Facebook ► 🤍 Nursing Facebook ► 🤍 Twitter ► 🤍 Instagram ► 🤍 Pinterest ► 🤍 LinkedIn ► 🤍
Official Ninja Nerd Website: 🤍 You can find the NOTES and ILLUSTRATIONS for this lecture on our website at: 🤍 Ninja Nerds! In this lecture Professor Zach Murphy will be presenting on Cholinergic Agonists. We hope you enjoy this lecture and be sure to support us below! Table of Contents: 0:00 Lab 0:07 Cholinergic Agonists Introduction 0:43 The Cholinergic System 11:11 Cholinergic Receptors and Agonists 32:56 Clinical Indications and Adverse Effects of Agonists 1:03:09 Cholinergic Agonists Practice Problems 1:16:32 Comment, Like, SUBSCRIBE! Pharmacology Source: Whalen, Karen. Lippincott Illustrated Reviews: Pharmacology (Lippincott Illustrated Reviews Series). Wolters Kluwer Health. Kindle Edition. Join this channel to get access to perks: 🤍 APPAREL | 🤍 🤍 PODCAST | Apple Podcast: 🤍 Spotify: 🤍 Google Podcast: 🤍 DONATE PAYPAL | 🤍 SOCIAL MEDIA FACEBOOK | 🤍 INSTAGRAM | 🤍 TWITTER | 🤍 🤍NinjaNerdSci DISCORD | 🤍 #ninjanerd #CholinergicAgonists #pharmacology
👉📝WANT STUDY NOTES FOR THIS PRESENTATION? 👉Join Patreon at 🤍 Cholinergic drugs are medications that inhibit, enhance, or mimic the action of the neurotransmitter acetylcholine, which is the primary transmitter of nerve impulses within the parasympathetic nervous system. This pharmacology lecture covers topics such as mechanism of action of cholinergic agonists, cholinergic receptors; muscarinic & nicotinic, direct-acting cholinergic agonists, indirect-acting cholinergic agonists (reversible & irreversible), cholinergic toxicity & adverse effects. Cholinergic drugs mentioned include: Acetylcholine, Carbachol, Pilocarpine, Bethanechol, Edrophonium, Physostigmine, Neostigmine, Pyridostigmine, Donepezil, Rivastigmine, Galantamine, Echothiophate. Thanks for watching and don't forget to SUBSCRIBE, hit the LIKE button👍 and click the BELL button🔔 for future notifications!!! 0:00 Cholinergic neuron 1:45 Cholinergic receptors 4:19 Types of cholinergic agonists 4:37 Direct-acting cholinergic agonists 6:41 Indirect-acting cholinergic agonists 9:50 Cholinergic adverse effects
👉📝WANT STUDY NOTES FOR THIS PRESENTATION? 👉Join Patreon at 🤍 Asthma and chronic obstructive pulmonary disease (COPD) are chronic lung diseases marked by an inflammation and narrowing of the airways. This pharmacology lecture discusses the basic pathophysiology of asthma and COPD as well as mechanism of action of various drugs used in treatment of these diseases. Drugs mentioned include: β2 adrenergic agonists - Albuterol, Levalbuterol, Arformoterol, Formoterol, Vilanterol, and Salmeterol; Muscarinic antagonists (anticholinergics) - Ipratropium, Tiotropium, Aclidinium and Umeclidinium; Leukotriene modifiers - Montelukast, Zafirlukast, and Zileuton; Phosphodisterase inhibitors - Theophylline and Roflumilast; Anti-IgE monoclonal antibody - Omalizumab; Antihistamines; Corticosteroids - Beclomethasone, Budesonide, Ciclesonide, Fluticasone, Mometasone, Triamcinolone, Dexamethasone, Methylprednisolone, Prednisone, and Prednisolone. Thanks for watching and don't forget to SUBSCRIBE, hit the LIKE button👍 and click the BELL button🔔 for future notifications!!! 00:00 Intro 00:24 Asthma pathophysiology 03:43 COPD pathophysiology 04:58 β2 adrenergic agonists 06:06 Muscarinic antagonists 07:09 Leukotriene modifiers 07:58 Phosphodisterase inhibitors 09:07 Anti-IgE antibody & Antihistamines 10:02 Corticosteroids
Introduction to Pharmacology V-Learning™ - 🩺 1800+ Lectures on sqadia.com ▶️ 🤍 🧾 Description - sqadia.com give you another informational lecture of Pharmacology. Whenever starting a new subject in a semester, have you ever wondered that what is its origin? What will I be learning in this subject? Of course, you have! So, today sqadia.com will resolve this problem of your and provide you introduction to clinical pharmacology. Watch this video till the end and get your concepts cleared today! 🕘 Timestamps - 00:00 - Introduction to Pharmacology 00:25 - What is Pharmacology? 02:20 - Drugs Classification 04:41 - Pharmacokinetics vs Pharmacodynamics 06:30 - Pharmacodynamics 07:48 - Route of Administration 08:37 - Route of Administration - Oral 09:08 - Route of Administration - Intravenous 10:00 - Route of Administration - Subcutaneous 10:39 - Route of Administration - Intramuscular 11:21 - Route of Administration - Transdermal 12:17 - Route of Administration - Rectal 12:52 - Route of Administration - Inhalation 13:41 - Route of Administration - Sublingual 15:07 - Pharmacokinetics Profile - ADME 15:22 - Pharmacokinetics Profile - Absorption 21:49 - Pharmacokinetics Profile - Distribution 22:58 - Pharmacokinetics Profile - Metabolism 25:26 - Pharmacokinetics Profile - Excretion 29:07 - Receptors - ion Channels 31:09 - Receptors - G-Protein Linked 32:26 - Receptors - Tyrosine Kinase-Linked 33:25 - Receptors - DNA-Linked 34:35 - Drug-Receptor interactions 34:57 - Drug-Receptor interactions - Agonist 35:19 - Drug-Receptor interactions - Antagonist 🎬 1800+ Medical Video Lectures Download sqadia.com Medical Students Apps today and start your Radiology Education - V-Learning™ is here! 📲 🤍 📲 🤍 🩺 About sqadia.com - Medical Students Online education 24/7/365. Get access to 30+ courses lectures, making learning easy. FREE Medical Online Videos - Sign Up Today! 🆓 🤍 👥 Social Media 🔔 Facebook - 🤍 🎞 Vimeo - 🤍 🔔 Pinterest - 🤍 📸 Instagram - 🤍 #pharmacology #pharmacist #pharma #epilepsy #medicalstudentsupdate #medicalschool #medicalstudy #medical #medicaleducation #medicalcollege
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Participate in the FREE online test for this lecture - 🤍 Download "Solution Pharmacy" Mobile App to Get All Uploaded Notes, Model Question Papers, Answer Papers, Online Test and other GPAT Materials - 🤍 This video is all about- Basic Introduction to Pharmacology | Definition, Historical landmarks and scope of pharmacology. Pharmacology is one of the most important branches in pharmacy, it deals with the study of the drug, drug's effect on the body and body responsible for the drug which has been taken is called pharmacology. Pharmacology has two main branches- (1) Pharmacodynamic and (2) Pharmacokinetic. The study of drugs or chemicals and the effects they have on living animals is called pharmacology. Pharmacology explains what drugs are, what they do to body functions and what the body does to them. Pharmacology also explains why a person may experience side effects when they take drugs and why there is such a wide spectrum of differences between drug actions in different people. Once the drug is bound to a protein it exerts a therapeutic effect on the body, this is the pharmacodynamics of a drug. There is an enormous list of different drugs and their actions in the body. Pharmacokinetics is the study of what happens to drugs once they enter the body. The main stages include: (1) The absorption of the drug into the blood and across cell membranes to enter the cells; (2) The distribution of the drug throughout the body (3) The metabolism or breakdown of the drug; and (4) The excretion of the drug from the body Solution-Pharmacy- The solution-Pharmacy is the completely dedicated channel for the Pharmacy Profession. Here we provide Free MCQs, Flashcard and Most Importantly Practical Videos for all Students. Find us in all leading Social Network to Stay Connected- Website- 🤍 Facebook Page- 🤍facebook.com/pharmavideo/ Facebook Group- 🤍 E-Mail- solutionpharmacy🤍gmail.com Instagram- 🤍 LinkedIn- 🤍
Pharmacology study tips for nursing students and medical students: This video discusses how to study for pharmacology in nursing school and gives study strategy tips and tricks on how to pass pharmacology. I give tips on how to make flash cards for pharmacology, studying pre-fixes & suffixes, study guides, and mnemonics. Nursing School Study Tips: 🤍 Article on How to Study for Pharmacology: 🤍
Today’s video is all about anti-infective drugs and antibiotic pharmacology for Nursing Students and NCLEX Review. For your FREE quiz and access to more full-length videos, click here: 🤍 After diagnosing bacterial infection, nurses use anti-infective drugs and antibiotics to treat infections caused by bacteria. Antibiotics and anti-infective drugs kill bacteria and prevent their growth. They can also be used to prevent bacterial infections in people who have been exposed. #NCLEX #pharmacology #pharmacology #RegisteredNurse #Antibiotics
👉📝WANT STUDY NOTES FOR THIS PRESENTATION? 👉Join Patreon at 🤍 Antiepileptic drugs, also referred to as anticonvulsants, are a diverse group of medications used in the treatment of epileptic seizures. Antiepileptics work in a number of different ways to inhibit or slow down neuronal firing to prevent seizures from occurring. This pharmacology lecture covers topics such as pathophysiology and classification of seizures, action potential, excitatory and inhibitory neurotransmission (role of glutamate and GABA), voltage-gated sodium and calcium channels, AMPA and NMDA receptors, mechanism of action and side effects of antiepileptic drugs. Drugs mentioned include; Carbamazepine, Oxcarbazepine, Lamotrigine, Phenytoin, Topiramate, Valproic acid, Zonisamide, Gabapentin, Pregabalin, Levetiracetam, Felbamate, Tiagabine, and Vigabatrin. Thanks for watching and don't forget to SUBSCRIBE, hit the LIKE button👍 and click the BELL button🔔 for future notifications!!! 0:00 Seizure classification 1:07 Excitatory synapse 2:44 Inhibitory neuron 3:51 Antiepileptics - mechanism of action 7:26 Side effects
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👉📝WANT STUDY NOTES FOR THIS PRESENTATION? 👉Join Patreon at 🤍 Antidepressants are drugs used for the treatment of major depressive disorders as well as other conditions including anxiety disorders, obsessive compulsive disorders (OCD), eating disorders, insomnia, post-traumatic stress disorder and some chronic pain. Most antidepressants act by increasing the synaptic availability of serotonin, norepinephrine, or dopamine. This pharmacology lecture covers topics such as monoamine hypothesis of depression, bipolar disorder, role of serotonin, norepinephrine, dopamine, monoamine receptors, mechanism of action of antidepressants; selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs), monoamine oxidase inhibitors (MAOIs), atypical antidepressants, and Lithium. Antidepressants mentioned include: Citalopram, Escitalopram, Fluoxetine, Fluvoxamine, Paroxetine, Sertraline, Venlafaxine, Desvenlafaxine, Duloxetine, Levomilnacipran, Amitriptyline, Amoxapine, Clomipramine, Desipramine, Doxepin, Imipramine, Maprotiline, Nortriptyline, Protriptyline, Isocarboxazid, Phenelzine, Tranylcypromine, Selegiline, Bupropion, Mirtazapine, Trazodone, Nefazodone, Vilazodone, and Vortioxetine. Thanks for watching and don't forget to SUBSCRIBE, hit the LIKE button👍 and click the BELL button🔔 for future notifications!!! 00:00 Monoamine Hypothesis 1:55 Overview 2:36 Serotonergic & Noradrenergic neurons 4:40 SSRIs 7:05 SNRIs 8:30 TCAs 10:52 MAOIs 13:44 Atypical Antidepressants 16:07 Lithium
#drnajeeb #pharmacology #medicines #adrenergic #drugs # adrenergicdrugs Adrenergic Drugs Part 1 | Pharmacology | Dr Najeeb Like this video? Sign up now on our website at 🤍 to access 800+ Exclusive videos on Basic Medical Sciences & Clinical Medicine. These are premium videos (NOT FROM YOUTUBE). All these videos come with English subtitles & download options. Sign up now! Get Lifetime Access for a one-time payment of $99 ONLY! Sign up now on our website at 🤍 - Why sign up for premium membership? Here's why! Membership Features for premium website members. 1. More than 800+ Medical Lectures. 2. Basic Medical Sciences & Clinical Medicine. 3. Mobile-friendly interface with android and iOS apps. 4. English subtitles and new videos every week. 5. Download option for offline video playback. 6. Fanatic customer support and that's 24/7. 7. Fast video playback option to learn faster. 8. Trusted by over 2M+ students in 190 countries. - Adrenergic Agonists are drugs that lead to stimulation of the adrenergic receptors. In doing so, adrenergic agonists generally simulate activation of certain aspects of the sympathetic nervous system and are thus also known as "sympathomimetics". Mechanisms of Action Overview A diverse variety of sympathomimetics exist which operate using distinct mechanisms. In general, these compounds are divided into direct-acting, indirect-acting, or mixed-acting agonists depending on whether they directly activate adrenergic receptors or do so by indirect mechanisms Direct-acting Agonists Direct agonists physically bind the adrenergic receptor and simulate binding of an endogenous ligand. These compounds can be highly specific, activating only certain subtypes of receptors, or can be rather promiscuous. Indirect-acting Agonists Indirect agonists do not physically bind adrenergic receptors. Instead, these compounds indirectly lead to receptor activation through a variety of possible mechanisms which include promoting release of endogenously-stored norepinephrine from presynaptic terminals as well as inhibition of norepinephrine re-uptake and degradation from the synapse. Mixed-acting Agonists Mixed agonists simply refer to those compounds which display both direct and indirect mechanisms of actions. As such, these compounds directly bind adrenergic receptors but also promote the indirect mechanisms described above. - Join this channel to get access to perks: Sign up now on our website at 🤍 🤍 Follow us on Facebook :- 🤍 Follow us on Instagram :- 🤍
This is the Arabic-English version of a series of lectures in clinical pharmacology by Dr. AM Fouda. This is lecture # 01 discussing drug receptors and consequences of drug binding - Clinical Pharmacology Dept, Mansoura Faculty of Medicine - 2016-2017. foudaamm🤍mans.edu.eg
Gastrointestinal (GI) diseases are those that affect any section of the gastrointestinal tract. There are many different types of GI diseases including gastroesophageal reflux disease (GERD), peptic ulcers, nausea & vomiting, constipation, and diarrhea. This pharmacology lecture discusses mechanism of action of various drugs used in treatment of GI illnesses i.e. H2-receptor antagonists, proton-pump inhibitors, antacids, mucosal protective agents, antiemetics, laxatives, and antidiarrheals. Thanks for watching and don't forget to SUBSCRIBE, hit the LIKE button👍 and click the BELL button🔔 for future notifications!!! Like what we do? Learn how to support us on Patreon! 💪🤍 0:00 Overview 2:28 Parietal cell acid secretion 3:34 H2-receptor antagonists 4:04 Proton pump inhibitors 4:50 Antacids 5:42 Mucosal protectants 7:21 Nausea and vomiting 8:11 Antiemetics 10:33 Laxatives 12:28 Antidiarrheals
Today’s video is all about heart failure pharmacology for Nursing Students and NCLEX Review. For your FREE quiz and access to more full-length videos, click here: 🤍 Heart failure is a condition in which the heart is unable to pump sufficient blood throughout the body. Many heart failure drugs can be used to treat it, and some of the most common ones are diuretics, ACE inhibitors, beta blockers, and nitrates. Heart failure can be caused by a variety of factors, including coronary artery disease, and high blood pressure. #NCLEX #pharmacology #CHFdrugs #HeartFailure #BetaBlockers #Diuretics #AceInhibitors #Pharmacologynursing
(USMLE topics) Diuretics, sympathetic inhibitors (sympatholytics), renin-angiotensin system blockers and vasodilators. This video is available for instant download licensing here: 🤍 Voice by: Ashley Fleming ©Alila Medical Media. All rights reserved. Support us on Patreon and get early access to videos and free image downloads: patreon.com/AlilaMedicalMedia All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition. Hypertension is most commonly associated with an increase in vascular resistance caused by narrower or stiffer blood vessels; but other mechanisms, including increased cardiac output, large blood volume, or excess venous return, are possible. These factors are the targets of antihypertensive agents, which can be grouped into several categories: - Diuretics, which promote sodium and water excretion by the kidneys and thereby decrease blood volume. - Medications that inhibit the sympathetic nervous system or the renin-angiotensin system. - And vasodilators, which dilate blood vessels, and thereby decrease vascular resistance. Of the three classes of diuretics used for treating hypertension, thiazides are the most commonly prescribed. Thiazides act on the distal tubule of nephrons, which reabsorbs only a small portion of the sodium load, so their diuretic effect is less powerful than that of loop diuretics, which act on the thick ascending limb of the loop of Henle. However, thiazides also have a vasodilation effect by an unknown mechanism. The two classes produce similar side effects, but the side effects are more severe with loop diuretics. Potassium-sparing diuretics act mainly in the collecting duct and have only a mild diuretic effect, but they can compensate for the potassium loss induced by other diuretics, and are therefore commonly used in conjunction with thiazide or loop diuretics. Sympathetic inhibitors, or sympatholytics, act on adrenergic receptors to block sympathetic activity. There are beta-blockers, alpha-blockers, mixed alpha and beta-blockers, and central sympatholytics. Beta blockers are typical first-line treatment for hypertension. They reduce heart rate and cardiac contractility and thus decrease cardiac output. Alpha-1 blockers are effective in reducing sympathetic vasoconstriction, but their action can lead to an excessive baroreceptor-mediated reflex that increases heart rate and produces tachycardia. Non-selective adrenergic antagonists block both alpha and beta receptors. By inhibiting beta receptors in the heart, they are able to lower blood pressure without inducing reflex tachycardia. Central sympatholytics stimulate alpha-2 receptors in the brainstem to reduce sympathetic tone. They reduce heart rate, contractility and vasoconstriction, but may also cause sedation. Renin-angiotensin system blockers include ACE inhibitors and angiotensin receptor blockers. ACE inhibitors are commonly used as first-line treatment for hypertension. They block the conversion of angiotensin-I to angiotensin-II, which in turn leads to a reduction in aldosterone. Their action reduces systemic vasoconstriction and increases sodium and water excretion by the kidneys. Angiotensin receptor blockers inhibit the effects of angiotensin-II. Their indications are similar to those of ACE inhibitors. Vasodilators include calcium channel blockers, direct arterial vasodilators and nitrodilators. Calcium channel blockers inhibit L-type calcium channels that are responsible for smooth muscle contraction, cardiac myocyte contraction, and action potential generation in cardiac nodal tissue. The dihydropyridine class acts on peripheral blood vessels. They are powerful vasodilators but their action can lead to reflex tachycardia and increased cardiac contractility. Non-dihydropyridine agents, on the other hand, primarily act to decrease heart rate, contractility and cardiac conduction speed; and are less effective on peripheral vessels. By having cardiac depressant effect, they can reduce blood pressure without producing reflex cardiac stimulation. However, they should not be used for patients with systolic heart failure. The mechanisms of direct arterial vasodilators are not entirely clear. They can cause reflex tachycardia and are only used for short-term treatment of refractory hypertension. Nitrodilators act by releasing nitric oxide, a powerful vasodilator. They are administered intravenously to manage hypertensive crises and to control blood pressure during surgery.
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This is part 1, be sure to also watch part 2. Both videos cover the important pharmacology concepts to know for NCLEX, ATI and Hesi nursing exams. Also, for more content visit Nexus Nursing on Tik Tok
Cathy shares key information about ipratropium, which is an inhaled/intranasal anticholinergic. Cathy Parkes BSN, RN, CWCN, PHN covers Ipratropium . The Pharmacology video tutorial series is intended to help RN and PN nursing students study for nursing school exams, including the ATI, HESI and NCLEX. #NCLEX #Ipratropium #Pharmacology #HESI #Kaplan #ATI #NursingSchool #NursingStudent #Nurse #RN #PN #Education Comments? Suggestions? Please share! Your feedback can help inform our future videos and study resources. 🙂 🤔🤔🤔 DO YOU WANT TO PASS your classes, proctored exams and the NCLEX? 🤔🤔🤔 Our flashcards are the best you can buy. They are built with a single goal: help you pass with no fluff. Everything you need, and nothing you don’t. Don’t take our word for it, though! Check out our hundreds of 5-star reviews from nurses who passed their exams and the NCLEX with Level Up RN. Our #Pharm #Pharmacology Flashcards are available at ➡️ 🤍 ✨Want perks? Join our channel! 🤍 👇SHOP ALL OUR FLASHCARDS👇 🤍 🗂️ Our NCLEX Pack is your #1 Resource to get through nursing school and to pass the NCLEX. Whether you are just starting school or you’re already prepping for the NCLEX, this bundle of flashcards is the best you can buy. It covers all the information you need to know to pass all your exams and it has FREE shipping! ➡️🤍 ⬅️ 📧 LOOKING FOR FREE RESOURCES TO HELP WITH YOUR EXAMS? Get exclusive tips, latest video releases and more delivered to your email! ➡️ 🤍 ⬅️ 👩⚕️ LEVEL UP NURSE SQUAD 👩⚕️ All of the nurses at Level Up RN are here to help! Cathy Parkes started helping her fellow classmates back when she was in nursing school, tutoring so they could pass their exams and graduate. After she got her BSN and started working as an RN at Scripps Encinitas Hospital, she started this YouTube channel to help nursing students around the world. Since then she has built a team of top-notch dedicated nurses and nurse educators who are focused on improving nursing education and supporting career advancement for nurses everywhere. With flashcards, videos, courses, organizational tools and more, we are singularly focused on helping students and nurses Level Up on their exams and nursing careers. 👋 STAY CONNECTED 👋 TikTok: 🤍 Instagram: 🤍 Facebook: 🤍 Pinterest: 🤍
Today’s video is all about psychiatric pharmacology and medications for Nursing Students and NCLEX Review. For your FREE quiz and access to more full-length videos, click here: 🤍 Psychiatric medications are used to treat a variety of mental health issues, such as schizophrenia, bipolar disorder, anxiety, and depression. As a nurse, you’ll need to administer psychiatric drugs to patients in your day-to-day. For real-world nursing and the NCLEX exam, you have to remember each psychiatric pharmacology class and their mechanisms of action. And we’re making memorization easy for you with plenty of mnemonics and examples in today’s video. #NCLEX #psychiatricnursing
Today’s video is all about Antiplatelet vs Anticoagulant Blood Thinners for Nursing Students and NCLEX Review. For your FREE quiz and access to more full-length videos, click here: 🤍 The difference between antiplatelet vs anticoagulant blood thinners is important – if you give the wrong one to a patient, it could be life-threatening. Antiplatelets work by preventing blood platelets from sticking together and forming clots. Anticoagulants, on the other hand, keep your blood from clotting too much. Blood thinners are often prescribed for patients with heart problems or other conditions requiring regular monitoring of blood flow throughout the body. #NCLEX #pharmacology #RegisteredNurse #Heparin #Warfarin
👉📝WANT STUDY NOTES FOR THIS PRESENTATION? 👉Join Patreon at 🤍 Opioids, sometimes called narcotics, are a group of drugs that act on the central nervous system to produce morphine-like effects such as pain relief and euphoria. This pharmacology lecture covers topics such as nociceptive pain pathway, role of glutamate, substance P, and calcitonin gene–related peptide (CGRP) in pain processing, endogenous opioids (enkephalins, endorphins, dynorphins), NMDA, AMPA, NK-1, CGRP receptors, opioid receptors (mu, delta, kappa) mechanism of action and side effects of narcotic drugs, development of opioid tolerance and addiction, partial mu-receptor opioid agonist and antagonist. Drugs mentioned include; Morphine, Fentanyl, Hydrocodone, Hydromorphone, Methadone, Meperidine, Oxycodone, Oxymorphone, Buprenorphine, and Naloxone. Thanks for watching and don't forget to SUBSCRIBE, hit the LIKE button👍 and click the BELL button🔔 for future notifications!!! 0:00 Nociceptive pain pathway 0:54 Neurotransmission of pain signal 2:57 Endogenous opioids & opioid receptors 4:32 Synthetic opioids 5:29 Side effects 7:19 Opioid addiction 8:50 Buprenorphine 10:02 Opioid antagonist - Naloxone
(USMLE topics) Mechanisms of action of cholinergic agonists and antagonists (anticholinergics): direct and indirect agonists (reversible and irreversible cholinesterase inhibitors), Botox, nicotinic and muscarinic antagonists. This video is available for instant download licensing here: 🤍 Voice by: Ashley Fleming ©Alila Medical Media. All rights reserved. Support us on Patreon and get early access to videos and free image downloads: patreon.com/AlilaMedicalMedia All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition. Acetylcholine is a major neurotransmitter of the nervous system. It is released by motor neurons at neuromuscular junctions to stimulate skeletal muscle contraction. Acetylcholine is also the primary neurotransmitter of the parasympathetic nervous system responsible for the body’s “rest and digest” state. It slows heartbeats, slows respiratory rate, contracts smooth muscles of the gastrointestinal tract and urinary bladder, stimulates various secretions, and constricts pupils. Acetylcholine is also active in several brain regions associated with cognition and movement. A neuron that uses mainly acetylcholine as neurotransmitter is called a cholinergic neuron. Acetylcholine is an ester of choline. It is synthesized and stored in the nerve terminal. When a cholinergic neuron is stimulated, acetylcholine is released into the synaptic cleft where it binds to its receptor on the postsynaptic cell, triggering cellular response. Acetylcholine is rapidly cleared from the synapse by the enzyme acetylcholinesterase, which binds to acetylcholine and hydrolyzes it into choline and acetate. The enzyme molecule quickly recycles itself each time, ready for another round of reaction. There are 2 main types of acetylcholine receptors: muscarinic and nicotinic, each type has several subtypes, or classes. Each receptor class is specific to certain synapses or tissues. Cholinergic agonists are drugs that mimic or enhance the action of acetylcholine, while cholinergic antagonists are those that inhibit its action. Because action of acetylcholine is widespread, cholinergic drugs may produce lots of side effects when administered systemically. Drugs that target a particular receptor class are more specific and are therefore preferred. Cholinergic agonists can be direct-acting or indirect-acting: Direct-acting agonists mimic acetylcholine, they bind to acetylcholine receptor and activate downstream signaling. They are not easily metabolized by acetylcholinesterase and therefore last longer at the synapse. Examples are drugs used as eye drops to constrict pupil and reduce intraocular pressure for treatment of glaucoma. Some agents are used to increase smooth muscle tone in urinary bladder and gastrointestinal tract, or to stimulate saliva secretion to treat dry mouth. Indirect agonists act by inhibiting the enzyme acetylcholinesterase, thereby increasing the concentration of acetylcholine available at the synapse. Reversible inhibitors form a transient, reversible complex with the enzyme. They slow down the recycling of the enzyme, making it less available for breaking down acetylcholine. Some of these drugs are used to treat myasthenia gravis, or to reverse the effects of anesthesia. Others are given to boost cholinergic activities in Alzheimer’s brain to compensate for the loss of functioning neurons. Irreversible cholinesterase inhibitors bind to the enzyme in an irreversible manner and permanently inactivate it. These drugs are very toxic, they are used as insecticides and “nerve gases”. Cholinergic antagonists inhibit acetylcholine action by several mechanisms: Botulinum toxin, Botox, is a bacterial toxin. It blocks acetylcholine release by inhibiting exocytosis. Botox is used to treat localized muscle spasms, movement disorders and strabismus. It is given by direct injection into the affected muscle. Nicotinic antagonists compete with acetylcholine for binding to nicotinic receptor. They are most commonly used to relax skeletal muscles during surgery. Muscarinic antagonists compete with acetylcholine for binding to muscarinic receptor. They are used to treat bradycardia, diarrhea and bladder spasms, dilate bronchi, reduce secretions, and dilate pupils. Some are used as sedatives and to counteract cholinesterase inhibitors.
👉📝WANT STUDY NOTES FOR THIS PRESENTATION? 👉Join Patreon at 🤍 Antibiotics, also known as antibacterials, are a group of drugs used to treat various infections caused by bacteria. Antibiotics work by either selectively killing (bactericidal) or inhibiting the growth (bacteriostatic) of bacteria. This pharmacology lecture covers topics such as classification of antibiotics; cell wall structure of Gram-negative bacteria, Gram-positive bacteria, Mycobacteria; mechanism of action and side effects of Cell Wall Synthesis Inhibitors: Beta-lactams (Penicillins, Cephalosporins, Carbapenems, Monobactams), Beta-lactamases (Avibactam, Clavulanic acid, Sulbactam, Tazobactam), Fosfomycin, Cycloserine, Vancomycin, Bacitracin, Antimycobacterial drugs (Isoniazid, Ethambutol), mechanism of action and side effects of Cell Membrane Integrity Disruptors: Daptomycin, Polymyxins. Thanks for watching and don't forget to SUBSCRIBE, hit the LIKE button👍 and click the BELL button🔔 for future notifications!!! Source of diagram depicting the enzymatic steps involved in S. aureus cell wall synthesis: 🤍 0:00 Intro 2:02 Bacterial cell wall structure 3:02 Beta-lactams & Beta-lactamases 6:18 Enzymatic steps of cell wall synthesis 8:24 Fosfomycin, Cycloserine, Vancomycin, Bacitracin 11:38 Mycobacterial cell wall inhibitors 14:24 Cell membrane integrity disruptors
🖼 🥰 Animated Mnemonics (Picmonic): 🤍 Lipid-Lowering Agents (aka antihyperlipidemic medications) are drugs that try to lower plasma lipoproteins (LDL, VLDL, Chylomicrons) and triglycerides (TGLs). Cholesterol-Lowering Agents include statins, niacin, fibrates, bile acid resins, ezetimibe, PCSK9 inhibitors, as well bempedoic acid. 🖼 🥰 Animated Mnemonics (Picmonic): 🤍 📱Save on your mobile phone bill: 🤍 🏦 Qbank (TrueLearn): 🤍
👉📝WANT STUDY NOTES FOR THIS PRESENTATION? 👉Join Patreon at 🤍 Benzodiazepines, barbiturates, and sedative-hypnotics are central nervous system depressants that work by enhancing the effects of the neurotransmitter gamma-aminobutyric acid (GABA), resulting in anxiolytic (anti-anxiety), hypnotic (sleep-inducing), anticonvulsant, and muscle relaxant properties. This pharmacology lecture covers topics such as pathophysiology of anxiety and insomnia, role of GABA in the central nervous system, structure and function of GABA-A receptor, limbic system, mechanism of action and side effects of benzodiazepines, barbiturates, and non-benzodiazepine sedative-hypnotics. Drugs mentioned include; Alprazolam, Chlordiazepoxide, Clonazepam, Diazepam, Lorazepam, Temazepam, Pentobarbital, Phenobarbital, Secobarbital, Zolpidem, Zaleplon, and Eszopiclone. Thanks for watching and don't forget to SUBSCRIBE, hit the LIKE button👍 and click the BELL button🔔 for future notifications!!! 0:00 Intro 0:28 GABA and its receptors 2:18 Limbic system 3:34 Benzodiazepines 5:18 Barbiturates 6:57 Nonbenzodiazepine hypnotics
In this video “Introduction to Pharmacology for Nursing Students” you will learn about: ► the definitions of pharmacology, pharmacokinetics and pharmacodynamics ► the 3 characteristics that a drug should ideally have ► the concept of reversibility of a drug ► the factors that determine how well a drug reaches its target site This video is part of the Lecturio course “Pharmacology: Pharmacology and Implications for Nursing” ► WATCH the complete course on 🤍 ► THE PROF: Rhonda Lawes is a Certified Nurse Educator (CNE) and Assistant Professor at the University of Oklahoma. She worked as a nurse manager at the Saint Francis Hospital and the Broken Arrow Medical Center. She has completed her Ph.D. in Educational Psychology at Oklahoma State University. ► LECTURIO is your smart tutor for nursing school: Learn the toughest NCLEX® topics with high-yield video lectures, integrated quiz questions, and more. Register now to study anytime and anywhere you want to: 🤍 ► CHECK OUT ALL NURSING COURSES: Leadership Nursing: 🤍 Dosage Calculation Nursing: 🤍 Physiology Nursing: 🤍 Medical Surgical Nursing: 🤍 Pharmacology Nursing: 🤍 NCLEX® Pharmacology Nursing: 🤍 Pediatric Nursing: 🤍 Study Skills Nursing: 🤍 Fundamentals of Nursing - Theory: 🤍 Fundamentals of Nursing - Clinical Skills: 🤍 Nursing Prerequisites: 🤍 Mental Health Nursing: 🤍 Nursing Care of Childbearing Family: 🤍 ► INSTALL the free Lecturio app iTunes Store: 🤍 Play Store: 🤍 ► SUBSCRIBE to our YouTube channel: 🤍 ► WATCH MORE ON YOUTUBE: 🤍 ► LET’S CONNECT: Facebook: 🤍 Instagram: 🤍 TikTok: 🤍tiktok.com/🤍lecturio_nursing #nursingschool #nursingeducation #pharmacology #nclex
Mechanisms of action of anticoagulant drugs: Heparin, Low-Molecular-Weight Heparin (LMWH), Warfarin (Vitamin K Antagonist - VKAs), and Direct Oral Anticoagulants (DOAs). Purchase PDF (video text + images) here: 🤍 Purchase a license to download a non-watermarked version of this video here: 🤍 Join this channel to get access to member-only videos and other perks: 🤍 ©Alila Medical Media. All rights reserved. Voice by : Marty Henne All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Anticoagulants are drugs used to reduce blood clotting, or coagulation. Coagulation is critical for the control of bleeding, which has 4 stages: - Stage 1: formation of platelet plugs. - Stage 2: formation of blood clots. Coagulation cascade produces thrombin and fibrin. - Stage 3: termination of clot formation. Antithrombin binds to thrombin, as well as several other clotting factors, and inhibits their function. - Stage 4: dissolution of blood clots. Medications that prevent formation of platelet plugs are antiplatelets. Medications that interfere with the function or synthesis of clotting factors are anticoagulants. Anticoagulants and antiplatelets are the 2 classes of antithrombotic drugs. Heparin binds to antithrombin and increases its affinity for thrombin and other clotting factors, thereby enhancing antithrombin’s inhibitory effect on coagulation, typically up to thousand-fold. Low-molecular-weight heparin is produced by chemically splitting heparin into pieces of about one-third of its original size. The smaller size reduces its non-specific binding to plasma proteins and blood components, resulting in fewer side effects, longer half-life, and a more predictable dose-dependent response, so monitoring is not usually required. However, the shorter chain length also reduces its ability to bridge between antithrombin and thrombin, producing a reduced inhibitory effect on thrombin. Its anticoagulation effect relies on inhibition of factor 10a, for which a specific five-saccharide motif is sufficient. Fondaparinux is a synthetic drug based on this five-saccharide sequence. It has a longer half-life and is associated with less bleeding complication than low-molecular-weight heparin in some studies. Vitamin K Antagonists, such as warfarin, act by inhibiting the enzyme required for activation of vitamin K. Vitamin K is an essential cofactor for the synthesis of many clotting factors. Direct oral anticoagulants are a new class of synthetic drugs that includes direct thrombin inhibitors and direct factor 10a inhibitors. The major adverse effect of all anticoagulants is uncontrolled bleeding. Reversal of anticoagulation: hemodialysis, red blood cells transfusion, platelet transfusion, activated charcoal to prevent absorption of the last dose of an oral anticoagulant. Certain anticoagulants have specific reversal agents that can counteract their effect. Heparin’s action can be reversed with protamine. Vitamin K, given orally or intravenously, can counteract warfarin. There are also specific antidotes for direct oral anticoagulants.
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👉📝WANT STUDY NOTES FOR THIS PRESENTATION? 👉Join Patreon at 🤍 Diuretics, commonly called water pills, are drugs that promote diuresis, that is increased production of urine. Diuretics work on the kidneys to eliminate water and electrolytes thus they have important applications in renal and cardiovascular disorders. This pharmacology lecture covers topics such as structure and function of nephron; afferent arteriole, Bowman's capsule, glomerulus, efferent arteriole, proximal convoluted tubule, loop of Henle, descending limb, ascending limb, distal convoluted tubule, collecting duct, principal cells, intercalated cells, aldosterone, antidiuretic hormone, reabsorption, secretion, urine production; Mechanism of action of diuretic drugs and their side effects; carbonic anhydrase inhibitors, loop diuretics, thiazide diuretics, potassium-sparing diuretics, and osmotic diuretics. Diuretics mentioned include; Acetazolamide, Bumetanide, Ethacrynic acid, Furosemide, Torsemide, Chlorothiazide, Chlorthalidone, Hydrochlorothiazide, Indapamide, Metolazone, Amiloride, Eplerenone, Spironolactone, Triamterene, Mannitol, and Urea. Thanks for watching and don't forget to SUBSCRIBE, hit the LIKE button👍 and click the BELL button🔔 for future notifications!!! 0:00 Nephron structure & function 3:58 Diuretics - overview 4:20 Carbonic anhydrase inhibitors 7:11 Loop diuretics 9:47 Thiazide diuretics 13:11 Potassium-sparing diuretics 16:30 Osmotic diuretics
👉📝WANT STUDY NOTES FOR THIS PRESENTATION? 👉Join Patreon at 🤍 Lipid-lowering agents, or hypolipidemic agents, are a group of drugs that are used in the treatment of high levels of fats, such as triglycerides and cholesterol, in the blood. Hyperlipidemia (also known as high cholesterol) is the key contributing factors to the development of atherosclerosis (hardening of the arteries), which can lead to stroke and heart attack. This pharmacology lecture covers topics such as pathophysiology of hyperlipidemia; lipids, cholesterol, triglycerides, phospholipids, bile acids, fatty acids, lipoproteins, apolipoproteins, chylomicrons, VLDL, LDL, HDL, lipoprotein lipase, atherosclerosis, and vascular inflammation; mechanism of action of lipid-lowering drugs and their side effects; HMG-CoA reductase inhibitors (statins), nicotinic acid, fibrates, bile acid sequestrants, cholesterol absorption inhibitors, pcsk9 inhibitors, omega 3 fatty acids. Drugs mentioned include; Atorvastatin, Fluvastatin, Lovastatin, Pravastatin, Rosuvastatin, Simvastatin, Niacin, Fenofibrate, Gemfibrozil, Colesevelam, Colestipol, Cholestyramine, Ezetimibe, Evolocumab, Alirocumab, Docosahexaenoic acid (DHA), Eicosapentaenoic acid (EPA), Icosapent ethyl, and Fish oil. Thanks for watching and don't forget to SUBSCRIBE, hit the LIKE button👍 and click the BELL button🔔 for future notifications!!! 0:00 Pathophysiology of hyperlipidemia 4:18 HMG-CoA reductase inhibitors - Statins 6:20 Nicotinic acid - Niacin 7:39 Fibrates 9:25 Bile acid sequestrants 10:51 Cholesterol absorption inhibitors 12:24 PCSK9 inhibitors 13:27 Omega−3 fatty acids
Join Now! 🤍 In part 2 of 3, Kendall Wyatt MD, RN will help you understand how using drug endings can help you master Pharmacology faster, alongside Picmonic's research-proven learning system.Then watch Part 3 (🤍 Part 2 covers antibiotics and other high-yield medications you need to know! Step 1: Get the playlist here: bit.ly/easypharm2 Step 2: Watch Part 3! bit.ly/pharmmadeeasy TRY PICMONIC FOR FREE ►🤍 Picmonic turns the information you need to know in nursing and medical school into unforgettable images and stories that are scientifically proven to increase memory retention! Join over 400,000 nursing and medical students using Picmonic’s Visual Learning Community to study and learn more effectively in less time. Picmonic is research-proven to increase test scores by 50% and long-term memory retention by 331% Picmonic for Nursing has you covered for your classes and the NCLEX® with subjects including Fundamentals, Pharmacology, Med-Surg, Anatomy, Physiology, Pediatrics, Obstetrics, Psychiatric, and more!. Picmonic for Medicine has you covered for USMLE Step 1 and Step 2 CK, with subject including Pathology, Pharmacology, Microbiology, Biochemistry, Psychiatry, Anatomy, Physiology, Epidemiology, and more! LET’S CONNECT! General Facebook ► 🤍 Nursing Facebook ► 🤍 Twitter ► 🤍 Instagram ► 🤍 Pinterest ► 🤍 LinkedIn ► 🤍 Google+ ► 🤍
Antihistamines are drugs that block the action of histamine. They are commonly used for the relief of allergy symptoms or for gastrointestinal conditions. This pharmacology lecture covers topics such as pathophysiology of allergic reaction, histamine and its actions, H1 and H2 histamine receptors, mast cells, parietal cells, mechanism of action of H1 and H2 antagonists. Drugs mentioned include first generation antihistamines; Brompheniramine, Chlorpheniramine, Clemastine, Cyproheptadine, Diphenhydramine, Doxylamine, Hydroxyzine, Meclizine, Promethazine; Second generation antihistamines; Cetirizine, Desloratadine, Fexofenadine, Levocetirizine, Loratadine, Azelastine, Olopatadine, Ketotifen; H2 blockers; Cimetidine, Famotidine, Nizatidine, and Ranitidine. Thanks for watching and don't forget to SUBSCRIBE, hit the LIKE button👍 and click the BELL button🔔 for future notifications!!! Like what we do? Learn how to support us on Patreon! 💪🤍 0:00 Pathophysiology of allergic reaction 2:00 Histamine receptors 3:41 H1 receptor blockers 7:14 H2 receptor blockers
Rational for treatment and prevention of angina. Mechanisms of action of beta-blockers, calcium channel blockers, and organic nitrates. Purchase PDF (video text + images) here: 🤍 Purchase a license to download a non-watermarked version of this video here: 🤍 Join this channel to get access to member-only videos and other perks: 🤍 ©Alila Medical Media. All rights reserved. Voice by : Marty Henne All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Angina is a major symptom of ischemic heart disease. It manifests as chest pain and is caused by reduced blood flow to the heart. Angina occurs when the heart’s demand for oxygen is greater than the oxygen supply it can get. Antianginal drugs aim to: - dilate coronary blood vessels to increase flow to the heart; - and/or reduce the heart’s workload to reduce oxygen demand, typically by reducing heart rate or contractility. Three drug classes are used in the treatment or prevention of angina: beta-blockers, calcium channel blockers, and organic nitrates. In addition, antiplatelet drugs such as aspirin may also be prescribed to prevent blood clots. - Beta-blockers bind to beta1-adrenergic receptors and block the sympathetic influences that act through these receptors. Sympathetic nerves release norepinephrine to increase SA node firing rate and cardiac conductibility at the AV node. Sympathetic activation increases cardiac output in situations that require energy, such as during physical activities. This is when the heart must work harder and angina may occur. Beta-blockers suppress sympathetic effects, decreasing heart rate and thereby reducing the heart’s workload. However, because beta-blockers also slow down conduction through the AV node, they may cause heart blocks. - Calcium-channel blockers block calcium channels that are responsible for action potential generation in the SA node, as well as contraction of cardiac myocytes and vascular smooth muscle. Blocking these channels results in a lower heart rate, reduced contractility of the heart, and vasodilation. The dihydropyridine class acts on blood vessels. They are powerful vasodilators but their action can lead to reflex tachycardia and increased cardiac contractility. Non-dihydropyridine agents, on the other hand, primarily act to decrease heart rate, contractility; and are less effective on blood vessels. Because of their cardiac depressant effect, they should not be used for patients with systolic heart failure. - Organic nitrates act by releasing nitric oxide, a powerful vasodilator. They dilate both arteries and veins, but primarily veins, and thus producing a major reduction in preload and a moderate reduction in afterload on the heart. They also inhibit coronary spasms. Sublingual nitroglycerin is a short-acting nitrate. It diffuses immediately into the bloodstream, producing a fast but short-lived action, and is therefore used for immediate angina relief. Long-acting nitrates, beta-blockers, calcium channel blockers, and antiplatelet drugs are used for prevention of angina, with beta-blockers typically being first-line therapy.
👉📝WANT STUDY NOTES FOR THIS PRESENTATION? 👉Join Patreon at 🤍 Pharmacodynamics is the study of the biochemical and physiological effects of drugs on the body, often described as “what the drug does to the body.” This pharmacology lecture covers topics such as ligand-gated ion channels, G protein-coupled receptors, enzyme-linked receptors, intracellular receptors, agonists, antagonists (full, partial, inverse, competitive, non-competitive), and therapeutic index. Thanks for watching and don't forget to SUBSCRIBE, hit the LIKE button👍 and click the BELL button🔔 for future notifications!!! 0:00 Intro 0:56 Receptor types 1:22 Ligand-gated ion channels 1:51 G protein-coupled receptors 4:23 Enzyme-linked receptors 5:32 Intracellular receptors 7:12 EC50 & Emax 8:41 Agonists 9:44 Antagonists 11:27 Therapeutic index
👉📝WANT STUDY NOTES FOR THIS PRESENTATION? 👉Join Patreon at 🤍 Anticoagulants, commonly referred to as blood thinners, are drugs that prevent or reduce coagulation of blood, prolonging the clotting time. Antiplatelet drugs, also known as a platelet aggregation inhibitors, decrease platelet aggregation and inhibit clot formation. These drugs play an important role in the treatment of various disorders such as myocardial infarction, thrombotic stroke and venous thromboembolism. This pharmacology lecture covers topics such as pathophysiology of blood clot formation and platelet function; activation, aggregation, cross-linking; ADP receptors, glycoprotein IIb/IIIa receptors, cyclooxygenase-1 (COX-1) enzyme, fibrinogen, fibrin mesh, coagulation cascade; intrinsic & extrinsic pathways, clotting factors, antithrombin, heparin induced thrombocytopenia, INR, plasmin, and plasminogen; mechanism of action of platelet inhibitors, anticoagulants, thrombolytic agents, and drugs used for treatment of bleeding. Drugs mentioned include; Aspirin, Clopidogrel, Ticagrelor, Ticlopidine, Prasugrel, Abciximab, Eptifibatide, Tirofiban, Heparin, low molecular weight heparins; Enoxaparin, Dalteparin, Protamine sulfate, Apixaban, Rivaroxaban, Univalent & Bivalent direct thrombin inhibitors; Argatroban, Dabigatran, Bivalirudin, Desirudin, Warfarin, Vitamin K, Alteplase, Reteplase, Tenecteplase, Urokinase, Streptokinase, Aminocaproic acid, Tranexamic acid. Thanks for watching and don't forget to SUBSCRIBE, hit the LIKE button👍 and click the BELL button🔔 for future notifications!!! 0:00 Platelet plug formation 2:04 Platelet aggregation inhibitors 5:34 Coagulation cascade 7:38 Anticoagulants 12:03 Warfarin 14:11 Thrombolytics